Notes

Slide Show

Outline

1	Diabetes, PDE-5 and The Endocrinology of ED
2	Male Sexual Chemistry
3
4	The Nitric Oxide Cascade
5	Reports of Erections With Placebo and Viagra
6	Efficacy of Sildenafil
7	Sildenafil-1 & 2Yr Phone Survey
8	Given Sildenafil corrects ED in most but not all men Some men do not sustain their initial positive sildenafil response Is sildenafil tachyphylaxis the cause? Are coexistent risk factors responsible? Does risk factor modification improve the response to sildenafil ?
9	ED-At Risk Populations Diabetes Mellitus Hyperlipidemia Testosterone deficiency HBP-Antihypertensive meds Depression-Antidepressant Rx. Neuropathy Tobacco EtOH Radical Prostatectomy Age
10	Effect of Age on Nocturnal Penile Tumescence
11	ED in Diabetes-Baseline Response at +12 Wk.
12	Sildenafil Response by DM Subgroup
13	ED in Diabetes-Sildenadil Response By Age
14	ED in Diabetes-12 Week Response
15	Glycemia-ED- Sildenafil
16	Low Testosterone
17	Normal Testosterone
18	“Drink provoketh the desire but taketh away the performance”*
19	Lipids and Rigi-Scan
20	Atorvastatin Effect on Penile Erections
21	ED Risk Factors
22	Structure of PDE5 inhibitors
23	Overall Selectivity of Tadalafil
24
25	Tadalafil-Treatment Effect on Successful Intercourse: SEP Q3†
26	Intercourse Success Rate With Tadalafil as a Function of Time†‡
27	Diabetes Tadalafil- Treatment Effect on Successful Intercourse: SEP Question 3†‡
28	Vardenafil Diabetes Study Diary Questions -Penetration & Maintenance
29	Percent Response in Diabetic Men with ED
30	PDE-5 Inhibitors and ED in Diabetic Men 1. The PDE-5 inhibitors can reverse ED in diabetic men 2. PDE-5 responsiveness not yet linked to Diabetic control 3. Differences in AE profiles and period of responsiveness may exist 4. The new PDE-5 inhibitors expand medical options for men with ED
31	Prospective Studies
32	2002-The Torch Passes
33